Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo

Clinoptilolite Properties in Vivo
Here, we review the scientific literature on the health effects and safety in medical applications of different clinoptilolite-based materials and propose some comprehensive, scientifically-based hypotheses on possible biological mechanisms underlying the observed effects on the health and body homeostasis. We focus on the safety of the clinoptilolite material and the positive medical effects related to detoxification, immune response, and the general health status.


  • Hi G,

    Zeolite is a hydrated aluminosilicate. Aluminium forms part of the zeolite structure but it is permanently bonded into the structure, making it unavailable and therefore harmless. Without the imbalance caused by the presence of aluminium, zeolite would not have the capacity for cation exchange and would not be able to take up heavy metals or other toxic matter.

    The following information comes from the Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo:

    In vivo, the acid concentrations of the intestine are substantially lower than those used in industrial activation process. For instance, gastric acid in the stomach contains HCl at 0.05–0.1 M. In such an environment, a certain release of Al species from the clinoptilolite surface may well be hypothesized even though aluminum from the clinoptilolite materials does not enter the blood or accumulate in the body as shown in athletes supplemented with zeolite-clinoptilolite supplement (Lamprecht et al., 2015) or healthy rats supplemented with different clinoptilolite materials (Kraljević Pavelić et al., 2017) where aluminum released into systemic circulation was observed only in rats supplemented with synthetic zeolite A. The latter effect was attributed to the zeolite A lower stability in the acidic pH relevant for the human intestine in comparison to clinoptilolite materials. In this study, authors also proved that clinoptilolite materials were efficient in the removal of aluminum from aluminum chloride-intoxicated rats in vivo.

    I hope this information assures you of clinoptilolite’s safety regarding its aluminium content but please let me know if you have any other questions. I have attached a file with further information about the heavy metal content of zeolite.

    Zeo Natural
  • Hello,

    I notice from your technical data sheet that aluminium constitutes 12.10% of the product. Is ingesting aluminium a good thing? Is there any published research in support of ingesting zeolite without the body taking up and (potentially) storing the aluminium content?


  • Hi Charles, You will find our technical data sheet here:

  • Hello,

    Just curious how much microns is the zeolitr products you contain?



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